A research conducted at University of California Irvine Medical Center has developed a new therapy that, if delivered endoscopically, in combination with radiation therapy and chemotherapy, can prove beneficial for patients suffering from advanced esophageal cancer. The new biological therapy (TNFerade), in which an agent preventing tumor is injected, was tried on 24 patients of the highly fatal form of cancer. The treatment has a non-replicating virus, engineered to deliver the gene for a protein that fights cancer.